Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...
Detection of circulating tumor cells (CTCs) in stage T3-4 and/or N positive rectal cancer (RC) patients undergoing neoadjuvant therapy followed by curative surgery. This is an ASCO Meeting Abstract ...
Sequence specific effects on DNA and cell damage with the PARP inhibitor olaparib (AZD2281) and carboplatin. This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract does ...
Environmental Health Perspectives, Vol. 101, Supplement 3: Environmental Mutagenesis in Human Populations at Risk (Oct., 1993), pp. 263-267 (5 pages) Mammalian germ cell stages exhibit differences in ...
Researchers have developed a method for preserving human primordial germ cell-like cells (PGCLCs) and allowing them to replicate without apparent limit while still maintaining their germ-cell-like ...
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250+ Scientists Are Building The Most Complex Map Of Human Genetic Mutations Ever Created
BETHESDA, Md. — Your body is quietly collecting genetic changes right now, and scientists want to map every single one. A massive new research network is launching the most ambitious genetic study ...
Investigators have employed mutant mice to study how the accumulation of genetic errors is managed during egg and sperm formation. Sometimes the best way to understand a biological process is to ...
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