Their findings, published online in Developmental Cell on April 22, focus on how temperature alters key epigenetic signals—chemical tags on DNA-packaging proteins that determine which genes are active ...
Programmable CRISPR tools are turning stem cell biology into something closer to software engineering, shrinking ...
As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as ...
Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...
SAN DIEGO, Dec. 09, 2024 (GLOBE NEWSWIRE) -- Fate Therapeutics, Inc. (FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell ...
An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialised immune cells. The discovery, published in ...
Can reprogramming our genes make us young again? A breakthrough in longevity research may be nearing its first human trials.
Astrocytes in the adult brain show cellular plasticity; however, whether they have the potential to generate multiple lineages remains unclear. Here, we perform in vivo screens and identify DLX2 as a ...