The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that's added to a chain of amino acids ...

Throughout history, many viral diseases have proven difficult to treat. However, recent research into synthetic drugs has given medical science powerful new tools to combat these pathogens. One ...

Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia. The ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled ...

As tough as medieval chainmail armor and as soft as a contact lens. This material is not taken from science fiction, it is a ...

The 2025 conference brings together leading academics and industry professionals to explore developments and challenges in the rapidly evolving field of nucleic acid medicines. By uniting researchers ...

An international team, including researchers from HSE University, has created the first comprehensive map of ...

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and G-quadruplexes (G4s)—that influence gene expression. Some drugs target these ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

This article explores limitations of chemical synthesis in high-throughput settings and the technical advantages enzymatic ...