Galactus, also known as the Gah Lak Tus, is the overarching antagonist of the 2007 superhero film Fantastic Four: Rise of the Silver Surfer, the second and final installment in Tim Story's Fantastic …

The Brotherhood of Yaotl, also known as the Stone Generals, are the main antagonists of the 2007 film TMNT and its videogame adaptation of the same name. The four Aztec generals turned to stone who …

Edward "Eddie" Brock Jr., later known as Venom, is the main antagonist of the 2007 superhero film Spider-Man 3, the third and final installment of Sam Raimi's Spider-Man trilogy, and the main …

Norrin Radd, also known as the Silver Surfer, is the titular deuteragonist of the 2007 Marvel superhero film Fantastic Four: Rise of the Silver Surfer, the second and final installment in Tim Story's Fantastic …

Mary Shaw is the main antagonist of the 2007 supernatural horror film Dead Silence. She is an undead ventriloquist who has lost her voice and seeks vengeance against the small town of Raven's Fair.

Blackheart is the main antagonist of the 2007 Marvel movie Ghost Rider. He is the malicious, demonic son of Mephisto who wanted to destroy Earth by spreading Hell's influence over the world.

Michael John "Stuntman Mike" McKay is the main antagonist of the 2007 Quentin Tarantino film Death Proof. While he is acclaimed by the public to be a legendary Hollywood stuntman, he is secretly a …

Brawl is a minor antagonist of the 2007 film Transformers and its video game adaption of the same name. He is a vicious Decepticon who served for Megatron.

General Aguila is the main antagonist of the 2007 animated film TMNT. He is one of Yaotl's generals until he and Yaotl's other three siblings were encased in stone.

Anders Allikmäe is the main antagonist of the 2007 Estonian film The Class (original title: Klass). He is a high-school bully who takes pleasure in tormenting people he considers inferior or weak.