Welcome to NCBI The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. About the NCBI | Mission | Organization | …

The NCBI is located in Bethesda, Maryland, and was founded in 1988 through legislation sponsored by US Congressman Claude Pepper. The NCBI houses a series of databases relevant to biotechnology …

With this update, the email feature will also require My NCBI login, and PubMed emails will only be sent to the email address associated with the My NCBI account.

Continue reading An Updated Bacterial and Archaeal Reference Genome Collection is Available! → GenBank Release 268.0 is Available! 26 Aug 2025 GenBank release 268.0 (8/18/2025) is now …

Jul 21, 2025 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and …

As a national resource for molecular biology information, NCBI's mission is to develop new information technologies to aid in the understanding of fundamental molecular and genetic processes that control …

Optimize for Highly similar sequences (megablast) Optimize for More dissimilar sequences (discontiguous megablast) Optimize for Somewhat similar sequences (blastn) Choose a BLAST …

Submit sequence data to NCBI archives, including GenBank, Sequence Read Archive (SRA), and Gene Expression Omnibus (GEO), to obtain accession numbers. Assembled and unassembled read data …

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Updated Full-Text Search Now Available NCBI has updated the PubMed Central (PMC) full-text search functionality and user experience.